Japanese Researchers Create Drug That Regrows Teeth, With Human Trials Coming

The era of getting false teeth may be coming to a close, with a new groundbreaking drug proving its effectiveness in animals.

Researchers at Kyoto University Hospital have been impressed by how well the drug, which deactivates the protein that normally suppresses tooth growth, works.

In development for well over a decade, the drug has been successfully tested on mice and ferrets, showing great success in regrowing lost teeth.

The human study takes place later this year, and will potentially be commercially available by 2030.

Via New Atlas:

“The world’s first human trial of a drug that can regenerate teeth will begin in a few months, less than a year on from news of its success in animals. This paves the way for the medicine to be commercially available as early as 2030.

The trial, which will take place at Kyoto University Hospital from September to August 2025, will treat 30 males aged 30-64 who are missing at least one molar. The intravenous treatment will be tested for its efficacy on human dentition, after it successfully grew new teeth in ferret and mouse models with no significant side effects.”